Stroke-Biomarkers.com

Diagnosis

Symbol Description Associations Endpoint Genecards
1N86 D-dimer D-dimer is a fibrin degradation product. It is increased in acute phase of ischemic stroke and is associated with a high risk of recurrence and with cardioembolic etiology. It has been also associated with poor outcome and mortality. Similar levels have been determined in both subtypes of stroke during acute phase. Stroke Link
O76038 SEGN High levels of secretagogin have been found in patients suffering from hypoxic brain injury. Similar levels have been determined in both subtypes of stroke during acute phase. Mimic Link
P01185 NEU2 Copeptin adds predictive information on functional outcome and mortality at long-term. Stroke Link
P02741 CRP Independent of other cardiovascular risk factors, elevated plasma CRP levels significantly predict the risk of future ischemic stroke and TIA in the elderly. In ischemic stroke patients, high CRP circulating levels within 24h from onset are associated with poor long-term functional outcome [2]. No clear association has been found with aetiological classification of ischemic stroke. No diferences at plasma levels between hemorragic and ischemic stroke. Stroke Link
P02768 ALBU Baseline Ischemia-Modified Albumin (IMA) blood levels may be a biomarker for early identification of acute stroke, but not to differentiate Ischemic from hemorrhagic stroke patients. On the other hand, serum albumin is decreased in those patients who die following a stroke. No significant association has been found between vWf levels and aetiological subtypes of ischemic stroke. No ignificant difference at plasma level between stroke subtypes. Stroke Link
P04271 S100B Higher levels of S100B in ischemic stroke patients than healthy controls, showing a trend to be higher in those patients with poor outcome at third month after stroke. Also, high S100B leves have been associated with hemorrhagic transformation and brain edema. No clear association has been found between S100B levels and aetiological classification of ischemic stroke. Higher plasma levels were found in intracerebral hemorrhage than ischemic stroke patients. Stroke Link
P09104 ENOG Similar levels have been determined in both subtypes of stroke during acute phase. Stroke Link
P14780 MMP9 Associated with BBB disruption. Positively correlated with stroke severity and infart volume within acute phase of ischemic stroke. Raised plasma MMP-9 in stroke patients than mimics. Its relationship with poor outcome is not clear. Similar levels have been determined in both subtypes of stroke during acute phase. Stroke Link
P16860 ANFB High circulating levels of BNP/NT-proBNP are associated with poor outcome after stroke, although only minor predictive value is added to clinical information [2]. High BNP levels indicate an embolic origin for stroke patients. Similar levels have been determined in both subtypes of stroke. Stroke, TIA Link
P22303 ACES Low cholinesterase activity in stroke patients who will die within 1 year. Control Link
P42574 CASP3 Downregulation of caspase-3 is associated with reduced brain damage in ischemic models. CASP3 is more elevated in stroke than mimics. Similar levels have been determined in both subtypes of stroke during acute phase. Stroke Link

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2020. Last update: 2018-02-02 14:48:58h.