Biomarker function:HDL play a key role in protecting against heart disease via their role in reverse cholesterol transport, or the transport of excess cholesterol out of the body. HDL are also part of the innate immune system due to their ability to bind a number of toxic substances in the blood. It has recently been associated with development of post-stroke infections in a large study [1].
Neurovascular unit:No
Intracellular location:Secreted
Body fluids:Plasma, Serum
Prot-prot interactions:Unknown
Inductors:Unknown
Inhibitors:Unknown
Signaling pathway:Unknown
Biological process:Immunity, Lipid metabolism
Comments:PubChem code is indicated as a reference (SID 53789179)
Associations:HDL cholesterol levels are used for vascular risk factors management in primary and secondary vascular prevention. It has recently been associated with development of post-stroke infections
References:1. RodrÃguez-Sanz A. High-density lipoprotein: a novel marker for risk of in-hospital infection in acute ischemic stroke patients? Cerebrovasc Dis 2013; 35: 291-297
