Pentraxin-related protein PTX3, TNF alpha-induced protein 5, TSG-14
Acute phase protein. Regulation of innate immune system and inflammation. Member of the pentraxin superfamily, together with CRP.
PTX3 levels might reflect the underlying burden of atherosclerosis .
1. Rolph MS et al. Production of the long pentraxin PTX3 in advanced atherosclerotic plaques. Arterioscler Thromb Vasc Biol 2002;22:e10-4.
Higher plasma PTX3 levels are associated with mortality after stroke.
Acute phase, Inflammatory response