• Synonyms:CD62 antigen-like family member E, Endothelial leukocyte adhesion molecule 1
  • Biomarker name:LYAM2
  • Gene name:SELE
  • Gene id:6401
  • Genecards link:
  • Biomarker function:Cell-surface glycoprotein having a role in immunoadhesion. Mediates in the adhesion of blood neutrophils in cytokine-activated endothelium through interaction with PSGL1/SELPLG. May have a role in capillary morphogenesis.
  • Neurovascular unit:Other:
  • Intracellular location:Membrane
  • Body fluids:Plasma, CSF
  • Prot-prot interactions:Yes:
  • Inductors:Unknown
  • Inhibitors:Unknown
  • Signaling pathway:Unknown
  • Biological process:Cell adhesion
  • Comments:-
  • Associations:E-selectin does not show significant differences in ischemic stroke patients comparet to patients with TIA when measured in plasma during the first 12 h after onset but is associated with increased risk of ischemic stroke. No significant association has been found between E-selectine levels and aetiological subtypes of ischemic stroke
  • References:-

Source articles by endpoint

Endpoint Articles
AtherothromboticCherian P, 2003;
Endpoint Articles
DisabilityRichard S., 2015;
Endpoint Articles
StrokePrugger C, 2013;

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2013. Last update: 2018-02-02 14:48:58h.