Stroke-Biomarkers.com

87

P09429

High mobility group protein B1, amphoterin

HMGB1

HMGB1

3146

http://www.genecards.org/cgi-bin/carddisp.pl?gene=HMGB1

DNA binding protein, mainly ssDNA. Member of the family of alarmins, molecules that signal tissue and cell damage. HMGB1 augments inflammation by binding RAGE and TLR receptors.

Neuron

false

Nucleus, Secreted

false

Plasma, Serum, CSF

false

Unknown

false

Unknown

false

Unknown

false

Unknown

false

-

-

Higher circulating levels of HMGB1 are associated with poor outcome 1 year after stroke.



public

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2020. Last update: 2018-02-02 14:48:58h.