Stroke-Biomarkers.com

79

P04275

von Willebrand factor

VWF

VWF

7450

http://www.genecards.org/cgi-bin/carddisp.pl?gene=VWF

Blood glycoprotein involved in the maintenance of hemostasis by adhering platelets to the sites of vascular injury. Chaperone for coagulation factor VIII.

Vessel, Extracellular matrix

false

Secreted

false

Plasma, Serum, Urine, CSF

false

Yes



Unknown

false

Unknown

false

Unknown

false

Defects on VWF protein result in impaired platelet aggregation, leading to hemorrhages (von Willebrand disease).

-

Higher circulating levels in stroke patients with functional disability at third month after the event. No significant association has been found between vWf levels and aetiological classification of ischemic stroke

Cell adhesion, Hemostasis

public

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2020. Last update: 2018-02-02 14:48:58h.