Stroke-Biomarkers.com

75

P02671

Fibrinogen

FIBA

FGA

2243

http://www.genecards.org/cgi-bin/carddisp.pl?gene=FGA

Fibrinogen polymerizes to form fibrin in the coagulation cascade after thrombin activation. Moreover, it is a cofactor in platelet aggregation.

No

false

Secreted

false

Plasma, Serum, Urine, CSF

false

Yes



Yes



Unknown

false

Unknown

false

Fibrinogen is an heterohexamer formed by α, β, and γ chains. It is synthesized in the liver. Fibrinogen is an inflammatory marker.

-

Higher levels of circulating fibrinogen are associated with long-term poor outcome and death after stroke and with increased risk of ischemic stroke, but not provides incremental value over traditional risk factors. The association between fibrinogen levels and aetiological subtypes of ischemic strokes is not concordant in different studies.

Acute phase, Hemostasis

public

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2020. Last update: 2018-02-02 14:48:58h.