Stroke-Biomarkers.com

62

P01584

Interleukin-1 beta, Catabolin,

IL1B

IL1B

3553

http://www.genecards.org/cgi-bin/carddisp.pl?gene=IL1B&search=IL-1beta

Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Microglia

false

Secreted

false

Plasma, Serum, CSF

false

Unknown

false

Unknown

false

Unknown

false

Unknown

false

-

-

Cytokines may contribute to both neurotoxicity and neuroprotection. IL1beta has been found elevated in ischemic stroke patients compared to mimics. No clear association has been found with aetiological classification of ischemic stroke

Inflammatory response

public

Neurovascular Research Laboratory - Vall d'Hebron Research Institute (VHIR). 2020. Last update: 2018-02-02 14:48:58h.